cells (in vivo examples). In HeLa cells in vitro, the force generated by a half-deformed mitotic cell is on the order of 50 to 100 nanonewtons. Internal hydrostatic pressure has been measured to increase from below 100 pascals in interphase to 3 to 10 fold that in mitosis.

In similar in vitro experiments, it was found that the threshold forces required to prevent mitosis are in excess of 100 nN.