the healing process from the injury is obtained. RFC5 and RCF2 are also engaged in DNA damage checkpoints and DNA replication checkpoints. Replication factor C is an emergency backup factor for DNA polymerases. RFC2 gene product required for a cell cycle checkpoint.

RFC is a heteropentamer in budding yeast, it is encoded either by RFC1 and RFC2-5 genes. For polymerases ? and ?, RFC is a primer recognition factor. During chromosomal DNA replication, the RFC2 gene product meets the RFC1 and RFC5 specific