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<p>and <a href="page.php?w=negative_strand_RNA_viruses">negative strand RNA viruses</a>. These viruses can form <a href="page.php?w=Budding">bud particle</a>s even in the absence of spike proteins by relying only on viral core components. The spike proteins can occasionally be produced as virus-like particles without the viral core. Therefore, optimal budding and release may be dependent on a coordinated "push-and-pull" action between core and spike, where oligomerization of both components is essential.</p>

<p><big>Effects on pathogenicity</big></p>
<p>Envelopes</p><p>
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