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Homeobox protein engrailed-1 is a protein that in humans is encoded by the EN1 gene.

Function

Homeobox-containing genes are thought to have a role in controlling development. In Drosophila, the engrailed (en) gene plays an important role during development in segmentation, where it is required for the formation of posterior compartments. Different mutations in the mouse homologs, En1 and

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