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<p><b>Heterotopic ossification</b> (<b>HO</b>) is the abnormal process by which <a href="page.php?w=bone_tissue">bone tissue</a> forms <a href="page.php?w=Heterotopia_%28medicine%29">outside of</a> the <a href="page.php?w=skeleton">skeleton</a> in muscles and soft tissue. It forms following a traumatic injury, neurogenic injury, or <a href="page.php?w=genetic_predisposition">genetic predisposition</a>. The likelihood and severity of HO is linked to the severity of the injury. The most common sites of developing HO are the hip, knee, elbow and shoulder.</p><p>
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