Ithaca ( ), also Ithaki ( ) or Ithaka ( Itháke ), is a Greek island located in the Ionian Sea, off the northeast coast of Kefalonia and to the west of continental Greece.

Ithaca's main island has an area of 96 km2 and in 2021 had a population of 2,862. It is the second-smallest of the seven main Ionian Islands,