Parvalbumin (PV) is a calcium-binding protein with low molecular weight (typically 9-11 kDa). In humans, it is encoded by the PVALB gene. It is a member of the albumin family; it is named for its size (parv-, from Latin ' which means "small") and its ability to coagulate.

It has three EF hand motifs and is structurally related to calmodulin and troponin C.