Port Charlotte is a census-designated place and unincorporated community in Charlotte County, Florida, United States. The population was 60,625 at the 2020 census, up from 54,392 at the 2010 census. It is included in the Sarasota metropolitan area.

Port Charlotte was named to the "10 Best Places to Retire", in the United States for the year 2012 by U.S. News & World Report.