In coagulation, the coagulation factor X can be activated into factor Xa in two ways: either extrinsically or intrinsically.

The activating complexes are together called tenase. Tenase is a blend word of "ten" and the suffix "-ase", which means, that the complex activates its substrate (inactive factor X) by cleaving it.

Extrinsic tenase complex is made up of tissue factor,

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