Terence Vincent Powderly (January 22, 1849 - June 24, 1924) was an American labor union leader, politician and attorney, who was the Grand Master Workman of the Knights of Labor from 1879 to 1893.

Born in Carbondale, Pennsylvania, he was later elected mayor of Scranton, Pennsylvania, for three 2-year terms, starting in 1878. A Republican, he served as the United States Commissioner General