The Panasonic Toughbook is a line of rugged computers produced and marketed by Panasonic. The first model, the CF-25, was introduced in 1996. The Toughbook brand mainly competes with other lines of rugged computers, such as Dell's Rugged Extreme.

In 2011, Panasonic introduced the Toughpad brand of ruggedized tablets, built to many of the same specifications as its Toughbook laptop