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Chordin (from Greek ?????, string, catgut) is a protein with a prominent role in dorsal-ventral patterning during early embryonic development. In humans it is encoded for by the CHRD gene.

History

Chordin was originally identified in the African clawed frog (Xenopus laevis) in the laboratory of Edward M. De Robertis as a key developmental protein that dorsalizes early vertebrate

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