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Haptocorrin (HC) (also known as transcobalamin-1 (TC-1), or cobalophilin) is a transcobalamin glycoprotein that in humans is encoded by the gene. It is essential to protect the acid-sensitive vitamin B₁₂ from degradation while in the stomach. It is also present in the serum where it binds most circulating vitamin B₁₂, rendering it unavailable for uptake

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