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<p><b>Heterochromatin</b> is a tightly packed form of chromatin, which comes in multiple varieties. These varieties lie on a continuum between the two extremes of <b>constitutive heterochromatin</b> and <b>facultative heterochromatin</b>. Both play a role in the <a href="page.php?w=gene_expression">expression of genes</a>, and correlate with late replication timing. Importantly, heterochromatin was once thought to be tightly coupled with structural compactness, phase separation and also deterministic transcriptional silencing. However, these notions</p><p>
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